Alfred Research Alliance Research Prize

The Alfred Research Alliance Research Prize (clinical and basic) is awarded annually for the best journal article describing original research which has been published in the previous calendar year.

These prestigious awards recognise just some of the leading research which is conducted across the Alfred Research Alliance each year. On this page, we salute our past winners, while looking forward to the ever-evolving excellence which is so much a part of life across the precinct.

To submit your journal article for consideration in this year’s awards, click below.

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Winner: Professor Dmitri Sviridov, Baker Heart & Diabetes Institute
Lake N, Taylor R, Trahair H, Harikrishnan KN , Curran J, Almeida M, Kulkarni H, Mukhamedova N, Hoang A, Low H, Murphy A, Johnson M, Dyer T, Mahaney M, Göring H, Moses E, Sviridov D, Blangero J, Jowett J (dec.) and Bozaoglu K. ‘TRAK2, a novel regulator of ABCA1 expression, cholesterol efflux and HDL biogenesis’ – European Heart Journal 2017;38(48):3579-87. [IF: 20.212]

Winner: Professor Jamie Cooper, Monash University, Intensive Care Unit, The Alfred

Cooper DJ, McQuilten Z, Nichol A, Ady B, Aubron C, Bailey M, Bellomo R, Gantner D, Irving S, Kaukonen KM, McArthur C, Murray L, Pettilä V, French C for the TRANSFUSE Investigators Australian & New Zealand Intensive Care Society Clinical Trials Group. ‘Age of red cells for transfusions and outcomes in critically ill adults’ – New England Journal of Medicine 2017;377(19):1858-67. [IF: 72.406].

Winner: Professor Paul Myles, Department of Anaesthesia & Perioperative Medicine, The Alfred, Monash University
Myles PS, Silbert B, Jayarajah M, Painter T, Cooper J, Marasco S, McNeil J, Bussières J, McGuinness S, Byrne K, Chan M, Landoni G and Wallace S (for the ATACAS Investigators of the ANZCA Clinical Trials Network).  ‘Tranexamic acid in patients undergoing coronary artery surgery’ New England Journal of Medicine 2017;376(2):136-48. [IF: 72.406]


Winner: Associate Professor Christoph Hagemeyer, Australian Centre for Blood Diseases, Monash University
Richardson JJ, Choy MY, Guo J, Liang K, Alt K, Ping Y, Cui J, Law LS, Hagemeyer CE, Caruso F. Polymer capsules for plaque-targeted in vivo delivery. Advanced Materials 2016 Sep;28(35):7703-7 [IF:18.960]

Winner: Professor Paul Myles, Department of Anaesthesia & Perioperative Medicine, The Alfred
Myles PS, Smith JA, Forbes A, Silbert B, Jayarajah M, Painter T, Cooper DJ, Marasco S, McNeil J, Bussières JS, Wallace S; ATACAS Investigators of the ANZCA Clinical Trials Network. Stopping vs. Continuing Aspirin before Coronary Artery Surgery. New England Journal of Medicine 2016;374(8):728-37 [IF:59.558]


Winner: Dr Michelle Boyle, Burnet Institute
Boyle MJ
, Reiling L, Feng G, Langer C, Osier FH, Aspeling-Jones H, Cheng YS, Stubbs J, Tetteh KK, Conway DJ, McCarthy JS, Muller I, Marsh K, Anders RF, Beeson JG. Human antibodies fix complement to inhibit Plasmodium falciparum invasion of erythrocytes and are associated with protection against malaria. Immunity 2015:42(3);580-90. [IF: 21.561]

Winner: Professor Jamie Cooper, Intensive Care Unit, The Alfred
Kaukonen KM, Bailey M, Pilcher D, Cooper DJ, Bellomo R. Systemic inflammatory response syndrome criteria in defining severe sepsis. New England Journal of Medicine 2015:372(17);1629-38. [IF: 55.873]


Winner: Dr Paul Gilson, Burnet Institute
Elsworth B, Matthews K, Nie CQ, Kalanon M, Charnaud SC, Sanders PR, Chisholm SA, Counihan NA, Shaw PJ, Pino P, Chan JA, Azevedo MF, Rogerson SJ, Beeson JG, Crabb BS*, Gilson PR*, de Koning-Ward TF*. PTEX is an essential nexus for protein export in malaria parasites. Nature 2014;511(7511):587-91 [IF: 41.456]

Winner: Professor Paul Myles, Department of Anaesthesia and Perioperative Medicine, The Alfred
Myles PS, Leslie K, Chan MT, Forbes A, Peyton PJ, Paech MJ, Beattie WS, Sessler DI, Devereaux PJ, Silbert B, Schricker T, Wallace S; ANZCA Trials Group for the ENIGMA-II investigators. The safety of addition of nitrous oxide to general anaesthesia in at-risk patients having major non-cardiac surgery (ENIGMA-II): a randomised, single-blind trial. Lancet 2014;384(9952):1446-54 [IF: 45.217]


Winner: Professor Fabienne Mackay, Department of Immunology, Monash University
Figgett WA, Fairfax K, Vincent FB, Le Page MA, Katik I, Deliyanti D, Quah PS, Verma P, Grumont R, Gerondakis S, Hertzog P, O’Reilly LA, Strasser A, Mackay F. The TACI receptor regulates T-cell-independent marginal zone B cell responses through innate activation-induced cell death. Immunity 2013;39(3):573-83. [IF:19.795]


Winner: Dr Xiaowei Wang, Baker IDI Heart and Diabetes Institute
Wang X
, Hagemeyer CE, Hohmann JD, Leitner E, Armstrong PC, Jia F, Olschewski M, Needles A, Peter K, Ahrens I. Novel single-chain antibody-targeted microbubbles for molecular ultrasound imaging of thrombosis: validation of a unique noninvasive method for rapid and sensitive detection of thrombi and monitoring of success or failure of thrombolysis in mice. Circulation. 2012;125(25):3117-26. [IF: 14.739]

Winner: Dr Tin Soe Kyaw, Baker IDI Heart and Diabetes Institute
Dinh TN, Kyaw TS, Kanellakis P, To K, Tipping P, Toh BH, Bobik A, Agrotis A. Cytokine therapy with interleukin-2/anti-interleukin-2 monoclonal antibody complexes expands CD4+CD25+Foxp3+ regulatory T cells and attenuates development and progression of atherosclerosis. Circulation. 2012;126(10):1256-66. [IF: 14.739]

Winner: Professor John Dixon, Baker IDI Heart and Diabetes Institute
Dixon JB, Schachter LM, O’Brien PE, Jones K, Grima M, Lambert G, Brown W, Bailey M, Naughton MT. Surgical vs conventional therapy for weight loss treatment of obstructive sleep apnea: a randomized controlled trial. JAMA. 2012;308(11):1142-9. [IF: 30.026]


Winner: Professor Jamie Cooper, Alfred Intensive Care Unit
Cooper DJ
, Rosenfeld JV, Murray L, Arabi YM, Davies AR, D’Urso P, Kossmann T, Ponsford J, Seppelt I, Reilly P, Wolfe R; DECRA Trial Investigators; Australian and New Zealand Intensive Care Society Clinical Trials Group. Decompressive craniectomy in diffuse traumatic brain injury. N Engl J Med 2011;364(16):1493-502. [IF: 53.484]

Winner: Dr Charbel Darido, Monash Central Clinical School
Darido C, Georgy SR, Wilanowski T, Dworkin S, Auden A, Zhao Q, Rank G, Srivastava S, Finlay MJ, Papenfuss AT, Pandolfi PP, Pearson RB, Jane SM. Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis. Cancer Cell 2011;20(5):635-48. [IF: 26.925]


Winner: Professor Murray Esler, Baker IDI Heart and Diabetes Institute
Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial. Symplicity HTN-2 Investigators, Esler MD, Krum H, Sobotka PA, Schlaich MP, Schmieder RE, Böhm M. Lancet 2010 Dec 4;376(9756):1903-9. [IF: 33.633]

Winner: Professor Markus Schlaich, Baker IDI Heart and Diabetes Institute
Renalase, a novel soluble FAD-dependent protein, is synthesized in the brain and peripheral nerves. Hennebry SC, Eikelis N, Socratous F, Desir G, Lambert G, Schlaich MMol Psychiatry 2010 Mar;15(3):234-6. [IF: 15.470]


Winner: Dr Andrew Davies, Alfred Intensive Care Unit
Australia and New Zealand Extracorporeal Membrane Oxygenation (ANZ ECMO) Influenza Investigators, Davies A, Jones D, Bailey M, Beca J, Bellomo R, Blackwell N, Forrest P, Gattas D, Granger E, Herkes R, Jackson A, McGuinness S, Nair P, Pellegrino V, Pettilä V, Plunkett B, Pye R, Torzillo P, Webb S, Wilson M, Ziegenfuss M. Extracorporeal membrane oxygenation for 2009 influenza A (H1N1) acute respiratory distress syndrome. JAMA 2009;302(17):1888-95. [IF: 30.718]


Winner: Professor Susan Davis, Women’s Health Program, Monash University
Davis SR, Moreau M, Kroll R, Bouchard C, Panay N, Gass M, Braunstein GD,
Hirschberg AL, Rodenberg C, Pack S, Koch H, Moufarege A, Studd J; APHRODITE Study
Team. Testosterone for low libido in postmenopausal women not taking estrogen.
N Engl J Med 2008 Nov 6;359(19):2005-17. [IF: 50.02]


Winner: Professor Jamie Cooper, Alfred Intensive Care Unit
SAFE Study Investigators; Australian and New Zealand Intensive Care Society
Clinical Trials Group; Australian Red Cross Blood Service; George Institute for
International Health, Myburgh J, Cooper DJ, Finfer S, Bellomo R, Norton R, Bishop
N, Kai Lo S, Vallance S. Saline or albumin for fluid resuscitation in patients with traumatic brain injury.
N Engl J Med 2007 Aug 30;357(9):874-84. [IF: 52.589]


Winner: Associate Professor Assam El-Osta, Baker Heart Research Institute
Harikrishnan KN, Pal S, Yarski M, Baker EK, Chow MZ, de Silva MG, Okabe J, Wang L, Jones PL, Sif S, El-Osta A. Reply to “Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex”. Nat Genet 2006; 38(9): 964-7. [IF: 25.797]


Winner: Professor Shaun Jackson, Australian Centre for Blood Diseases
Jackson SP, Schoenwaelder SM, Goncalves I, Nesbitt WS, Yap CL, Wright CE, Kenche V, Anderson KE, Dopheide SM, Yuan Y, Sturgeon SA, Prabaharan H, Thompson PE, Smith GD, Shepherd PR, Daniele N, Kulkarni S, Abbott B, Saylik D, Jones C, Lu L, Giuliano S, Hughan SC, Angus JA, Robertson AD, Salem HH.
PI 3-kinase p110beta: a new target for antithrombotic therapy. Nat Med 2005;11(5):507-14. [IF: 28.878]


Winner: Professor Jamie Cooper, Alfred Intensive Care Unit
Cooper DJ, Myles PS, McDermott FT, Murray LJ, Laidlaw J, Cooper G, Tremayne AB, Bernard SS, Ponsford J; HTS Study Investigators. Prehospital hypertonic saline resuscitation of patients with hypotension and severe traumatic brain injury: a randomized controlled trial. JAMA 2004;291:1350-7. [IF: 24.831]